1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE

1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE

2,4-dihydro-4-[(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazole-3-one

CAS: 106461-41-0

Molecular Formula: C22H27N5O2

1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE - Names and Identifiers

Name	2,4-dihydro-4-[(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazole-3-one
Synonyms	Itraconazole Hydroxy Isobutyltriazolone Itraconazole Hydroxy Isobutyltriazolone IMpurity 1-sec butyl-[4[4(4-hydroxyphenyl)-1-piperazinyl]-phenyl]-1,2,4-triazolo-5-one 2-butan-2-yl-4-[2-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-1,2,4-triazol-3-one 2-sec-butyl-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-2h-1,2,4-triazol-3(4h)-one 2-sec-butyl-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-2h-1,2,4-triazol-3(4H)-one 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 1-(sec-butyl)-4-(2-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one 2-sec-butyl-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2,4-dihydro-[1,2,4]triazol-3-one 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol- 2,4-dihydro-4-[(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazole-3-one 2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]-phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazole-3-one 2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl)Phenyl]-2-(1-Methyl Propyl)-3H-1,2,4-Triazole-3-One.
CAS	106461-41-0
EINECS	434-820-9
InChI	InChI=1/C22H27N5O2/c1-3-17(2)27-22(29)26(16-23-27)20-6-4-18(5-7-20)24-12-14-25(15-13-24)19-8-10-21(28)11-9-19/h4-11,16-17,28H,3,12-15H2,1-2H3

1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE - Physico-chemical Properties

Molecular Formula	C22H27N5O2
Molar Mass	393.48
Density	1.25±0.1 g/cm3(Predicted)
Melting Point	177-179°C
Boling Point	587.9±60.0 °C(Predicted)
Flash Point	309.4°C
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Vapor Presure	2.03E-14mmHg at 25°C
Appearance	Solid
Color	Off-White Pale Brown
pKa	12.18±0.30(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.647

1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE - Risk and Safety

Hazard Symbols	Xn - Harmful N - Dangerous for the environment
Risk Codes	R48/22 - Harmful danger of serious damage to health by prolonged exposure if swallowed. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Description	S2 - Keep out of the reach of children. S22 - Do not breathe dust. S36 - Wear suitable protective clothing. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.

1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE - Reference Information

Application	2, 4-dihydro-4-[[4-(4-hydroxyphenyl)-1-piperazinyl] phenyl]-2-(1-methylpropyl)-3H-1,2, 4-triazol-3-one can be used as organic synthesis intermediates and pharmaceutical intermediates, it is mainly used in the laboratory research and development process and chemical production process, and is mainly used in the synthesis of itraconazole.
use	intermediates synthesized by itraconazole.

Last Update：2024-04-09 02:00:05

1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE

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Product Name: 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE Visit Supplier Webpage Request for quotation
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Shanghai Yuanye Bio-Technology Co., Ltd.

Spot supply

Product Name: 2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE Visit Supplier Webpage Request for quotation
CAS: 106461-41-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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Wechat: 18301782025

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1-SEC BUTYL-[4[4(4-HYDROXYPHENYL)-1-PIPERAZINYL]-PHENYL]-1,2,4-TRIAZOLO-5-ONE

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